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Although anti-fibrotic drugs (such as pirfenidone) possess immunomodulatory potential, their role in chronic MPP injury remains unclear

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Beyond Lactobacillus and Bifidobacterium , several other taxonomic groups demonstrate significant therapeutic and industrial value ( Table 2 )

Efficacy of Probiotic Supplements on Brain-Derived Neurotrophic Factor, Inflammatory Biomarkers, Oxidative Stress and Cognitive Function in Patients with Alzheimers Dementia: A 12-Week Randomized, Double-Blind Active-Controlled Study

In diabetic complications, endogenous H 2 S deficiency correlates with chronic NF-B hyperactivation (wounds, osteoarthritis), impaired Nrf2 signaling (atherosclerosis), and defective mitophagy (nephropathy)